1/27/2024 0 Comments Increased physiologic dead space![]() The dead-space fraction was also independently associated with an increased risk of death in the multiple-regression analysis. The risk of death increased as the dead-space fraction increased. The mean dead-space fraction was significantly higher in patients who died than in those who survived (0.67☐.08 vs. Various physiological parameters including dead space fraction, airway resistance, static and dynamic pulmonary compliance, peak inspiratory pressure and positive end-expiratory pressure were measured. Patients were followed up until ICU discharge or demise. All patients were subjected to Full medical history, general examination, arterial blood gases, laboratory investigations, chest imaging, echocardiography and assessment by Acute physiology and chronic health evaluation (APACHE II) and Lung injury scoring. Methods: The study included 30 patients admitted to the ICU with ARDS. Objectives: to study the physiological dead space fraction and various physiological parameters in mortality prediction for patients with ARDS. Moreover, sustained elevation of VD/VT in ARDS has been associated with higher mortality. Newer evidence indicates that VD/VT is markedly elevated within 24 h of acute respiratory distress syndrome (ARDS) onset and is significantly elevated in non-survivors. ![]() ![]() Background: Physiologic dead-space fraction (DSF) (ratio of dead space to tidal volume ) is the portion of tidal volume that does not participate in gas exchange.
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